Durham are missing Steve Harmison and Graham Onions who are on England Lions duty against the Australians this week.
However, Worcestershire are even worse off as a result of that match, with Stephen Moore, Vikram Solanki and Steven Davies all absent.
Durham are looking for their fourth successive Championship victory and it is a brave man who will bet against them given bottom'club Worcestershire's problems so far this season.
Durham team
M Davies, WR Smith*, GJ Muchall, CD Thorp, MJ Di Venuto, ID Blackwell, KJ Coetzer, P Mustard†, DM Benkenstein, ME Claydon, LE Plunkett
Worcestershire team
MS Mason, GJ Batty*, DKH Mitchell, Kabir Ali, JPT Knappett†, DA Wheeldon, MM Ali, AA Noffke, BF Smith, CD Whelan, AN Kervezee